ABSTRACT
Background: Abnormal uterine bleeding (AUB) is a common gynaecological complaint associated with considerable morbidity. It significantly affects the patient’s family personal and social life. The aim of this study was to analyse the histopathological patterns of endometrium in patients presenting with AUB.Methods: This is a retrospective study conducted in the teaching hospital in the department of obstetrics and gynecology along with the pathology department. All patients with AUB were included in the study. This study of 138 samples both from hysterectomy specimens and endometrial biopsy were included.Results: The specimen obtained for examination of the endometrial samples 86 comprised from dilatation and curettage and rest 52 samples were obtained from hysterectomy specimens. Most common histopathological pattern was found to be proliferative endometrium, followed by disordered proliferative endometrium and atropic endometrium.Conclusions: Study of the histopathological pattern of the endometrial biopsies can be included in the initial evaluation of women with AUB when the cause of bleeding is not known along with ultrasound examination, then using it as the last modality for diagnostic and therapeutic purposes, irrespective of age group.
ABSTRACT
Background: Knowledge regarding the screening test (Pap smear) among women has been proven to be a significant predictor of first-time screening and in turn helps in early diagnosis and treatment of the disease. Hence this study was conducted to assess the knowledge and practice of pap smear screening test for cervical cancer among the women attending the outpatient department of obstetrics and gynecology.Methods: The cross-sectional study was conducted by the department of obstetrics and gynecology, at Sri Muthukumaran Medical College Hospital and Research Institute, among the women attending the outpatient department, during the month of August 2019. A total of 180 participants were included in the study. Data was entered in Microsoft excel and data analysis was done using statistical package for social sciences (SPSS) version 17.Results: Knowledge about carcinoma cervix and pap smear were present among 86.7% and 74.4% of participants, respectively. About the practice of pap smear, only 24.4% of the study participant have undergone the screening test and only two participants had taken the HPV vaccine.Conclusions: Most of the women had poor attitude and practice related to screening and vaccination for cervical cancer. But their attitude is favorable for screening. Hence promotion of free regular health check-up and vaccination for cervical cancer among general population might increase the awareness and decrease the disease burden.
ABSTRACT
Background: Medical students are at high risk for developing menstrual irregularities due to their lifestyle, food pattern and exercise habits. Also, majority of the menstrual disorders are preventable by changing better lifestyle, early diagnosis and treatment. Hence this study was conducted with the objective of addressing the menstrual disorders and associated problems among the medical students.Methods: The cross-sectional study was conducted by the department of obstetrics and gynaecology, at Sri Muthukumaran Medical College Hospital and Research Institute, among the first, second- and third-year female students who are doing their MBBS course in the same institute, during the month of December 2019. A total of hundred students were included in the study. Data was collected using a proforma and analysis was done using Statistical Package for Social Sciences (SPSS) version 17.Results: Menstrual cycle periodicity was irregular among 17% of participants. Dysmenorrhoea, mid cycle pain, heavy menstrual bleeding was noted among 27%, 19% and 11% respectively. Also 10% of students reported sickness absenteeism due to menstrual disorders.Conclusions: Adolescent students should be educated on the importance of physical and mental health in terms of healthy food habits and regular physical exercise to overcome the menstrual disorders and to enjoy healthy reproductive period.
ABSTRACT
Merremia emarginata Burm. F (Convolvulaceae) is a perennial, much branched herb (creeper). It is found widely distributed all over the India, specially in damp places in upper gangetic plain, Gujarat, Bihar, West Bengal, Western‐ Ghats, ascending up to 900m in the hills, Goa, Karnataka in India, Ceylon and Tropical Africa. Merremia emarginata is also known as Ipomoea reniformis chois. It is reported to have many important medicinal properties. In the Indigenous system of Medicine, Ipomoea reniformis has been claimed to be useful for cough, headache, neuralgia, rheumatism, diuretic, inflammation, troubles of nose, fever due to enlargement of liver and also for treating cancer. The present study was designed to evaluate the invitro anticancer activity of Merremia emarginata Burm.F. The different solvent fraction of whole plant Merremia emarginata Burm.F was subjected for MTT assay. The ethylacetate fraction of whole plant was found to be cytotoxic against human cervical carcinoma Hela cell lines and human breast carcinoma MCF cell lines. The IC50 value of ethylacetate fraction was 51.57μg/ml against Hela cell lines and 39.6μg/ml against MCF-7 cell lines. Significant results were observed thereby justifying the use of plant in the traditional system of medicine.